Contract Research

inviCRO’s contract research and image analysis services combine expertise in imaging study design and execution with advanced high-throughput image processing and analysis. inviCRO works with drug development teams to integrate novel anatomical and molecular imaging tools into preclinical and clinical research programs to assess drug and biomarker pharmacokinetics, distribution, targeting and activity to guide candidate and dose selection.

A study package may include any combination of the following:

inviCRO and our partner facilities also provide in vitro/ex vivo analysis to support imaging studies, e.g., ex vivo biodistribution, autoradiography, histology, and radioactive cell binding assays. We support the incorporation of these results into pharmacokineticsmodeling efforts as well as unique 3D merging of autoradiography and histology using our VivoQuant™ software platform.

Over the past few years, inviCRO has processed more than 25,000 tomograms from imaging studies that have crossed nearly every therapeutic category in a wide range of species including rodents, rabbits, ferrets, dogs, and non-human primates. In addition, we support advanced image analysis of first-in-human clinical studies. Our extensive hands-on experience performing studies with a wide range of imaging agents, animal models and instrumentation combined with our unique capabilities in imaging physics, advanced biostatistics, multi-dimensional image processing, and advanced analysis enable our clients to achieve their research goals.

Cost-efficient pilot studies, large-scale multi-cohort studies and multi-modality studies are available with full IP protection on novel compound testing. Recent studies managed or supported by the inviCRO team include: radiolabeled antibody, protein, and peptide imaging studies, glucose metabolism studies, dynamic (SPECT and PET) and functional (MRI) brain imaging studies, gated cardiac and lung deposition studies.

Collected study data integrates seamlessly with inviCRO's software platforms. Clients are kept apprised of study progress in real-time through a remote interface with the web-based iPACS® system.